A 10T/pixel CMOS digital pixel sensor with clock count output, ultra low supply voltage, and wide dynamic range is presented. The pixel fabricated by a standard 0.25-μm CMOS logic process comprises a reset transistor, a photo-diode, a comparator, and an inverter with pixel size of 9.4 × 9.4 μm2 and 24% fill factor. The amplified logarithmic output response similar to the light response of human eye is demonstrated in this work. The pixel can operate at a supply voltage as low as 1.2 V without affecting its output characteristics. The dynamic range of this cell limited by either the subsequent analog-to-digital circuit resolution or the rising and falling time of output clock is higher than 90 dB with an 8-bit resolution. c 2006 IEEE.