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    National Tsing Hua University Institutional Repository > 原子科學院  > 工程與系統科學系 > 會議論文  >  In vitro SIRC rabbit cornea cells growth on PDMS thin membrane under shear stress force


    Please use this identifier to cite or link to this item: http://nthur.lib.nthu.edu.tw/dspace/handle/987654321/47192


    Title: In vitro SIRC rabbit cornea cells growth on PDMS thin membrane under shear stress force
    Authors: Tseng, F.G.;Huang, H.;Chen, T.J.;Chang, H.Y.;Hu, Y.J.;Huang, C.Y.;Chieng, C.C.
    教師: 曾繁根
    Date: 2002
    Publisher: Institute of Electrical and Electronics Engineers
    Relation: Molecular, Cellular and Tissue Engineering, 2002. Proceedings of the IEEE-EMBS Special Topic Conference on, 6-9 June 2002, Pages 161 - 162
    Keywords: shear stress environment
    SIRC
    Abstract: This paper investigates cell growth behavior under a shear stress environment. SIRC rabbit cornea cells were grown on a silicon rubber membrane fabricated by micro molding technology. The membrane was clamped inside a stress apparatus, and air pressure was employed to apply shear stress on the silicone rubber membrane for cell growth testing. Different air pressures, from 0.4, 0.7, 1.0 to 1.8 Psig (2.76×103~1.24×104 Pa, gauge pressure), were applied on the membrane to generate steady shear strain on cell for more than 18 hours, respectively. The results showed the decrease of cell multiplication for the increase of air pressure on the membrane. A large decrease of cell multiplication at around 0.7 Psig suggested the turning point of cell growth behavior, and this point was also observed from the morphology change of the cell at the similar pressure level. This result will be beneficial for the growth control of corneal tissue
    URI: http://www.ieee.org/
    http://nthur.lib.nthu.edu.tw/dspace/handle/987654321/47192
    Appears in Collections:[工程與系統科學系] 會議論文

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