English  |  正體中文  |  简体中文  |  Items with full text/Total items : 54367/62174 (87%)
Visitors : 13878592      Online Users : 57
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTHU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version
    National Tsing Hua University Institutional Repository > 原子科學院  > 工程與系統科學系 > 會議論文  >  Binding efficiency improvement of antibody to antigen on mixed self-assembly monolayers


    Please use this identifier to cite or link to this item: http://nthur.lib.nthu.edu.tw/dspace/handle/987654321/47200


    Title: Binding efficiency improvement of antibody to antigen on mixed self-assembly monolayers
    Authors: Chun-Lung Wu;Yu-Wen Lin;Yi-Lin Hsu;Fan-Gang Tseng;Ching-Chang Chieng
    教師: 錢景常
    Date: 2005
    Publisher: Nano Science and Technology Institute
    Relation: 2005 NSTI Nanotechnology Conference and Trade Show. NSTI Nanotech 2005, 2005, p 359-62
    Keywords: atomic force microscopy
    biochemistry
    biotechnology
    molecular biophysics
    molecular orientation
    monolayers
    nanopatterning
    proteins
    self-assembly
    surface plasmon resonance
    Abstract: Protein chip is a potential tool on advanced disease diagnosis and drug screening, due to the capabilities of parallel process and trace-amount sample detection. The detection of proteins mainly depends on immune recognition, very sensitive to the orientation of immobilized proteins on solid surface. However, due to close packing of immobilized proteins on SAMs, the binding efficiency is usually lower than 10%. This paper proposed a novel way by employing mixed SAMs to generate nano patterns for effective separation of immobilized proteins to allow antibody conjugation from more directions. Testing results by Surface Plasma Resonance (SPR) and Atomic Force Microscope (AFM) investigation demonstrated a almost 3 fold increment on binding efficiency of protein immobilization on mixed SAMs
    URI: http://www.nsti.org/BioNano2005/showabstract.html?absno=1166
    http://www.nsti.org/
    http://nthur.lib.nthu.edu.tw/dspace/handle/987654321/47200
    Appears in Collections:[工程與系統科學系] 會議論文

    Files in This Item:

    File Description SizeFormat
    index.html0KbHTML747View/Open


    在NTHUR中所有的資料項目都受到原著作權保護,僅提供學術研究及教育使用,敬請尊重著作權人之權益。若須利用於商業或營利,請先取得著作權人授權。
    若發現本網站收錄之內容有侵害著作權人權益之情事,請權利人通知本網站管理者(smluo@lib.nthu.edu.tw),管理者將立即採取移除該內容等補救措施。

    SFX Query

    與系統管理員聯絡

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback